Women


Using foreskin tissue from newborn circumcisions, a group of researchers have identified a potential cellular mechanism that connects a mother’s smoking while pregnant with an increased risk of offspring obesity later in life.

Obesity is considered an epidemic in the U.S., with nearly 35 percent of adults and 20 percent of children six to 19 years old deemed obese. Obesity is a serious economic burden as well: more than $150 billion is spent annually on obesity-related healthcare costs in the U.S. alone.

“It has been consistently shown that mothers who smoke during pregnancy confer increased risk of obesity to their baby, but the mechanisms responsible for this increased risk are not well understood,” said the study’s principal investigator Kevin Pearson of the University of Kentucky (UK). “These data mark a first step towards defining those mechanisms with an eye toward potential interventions in the longer term.”

In collaboration with UK’s Department of Obstetrics and Gynecology, a total of 65 new mothers were recruited for the study in two different cohorts: 46 in Cohort 1 (2012-2013) and 19 in Cohort 2 (2015-2016). All of the infants were full-term; approximately half of all new mothers reported smoking during their pregnancies. DNA and RNA were isolated from foreskin tissue which would otherwise be discarded after routine circumcisions and analyzed with a focus on chemerin gene expression.

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Chemerin is a protein that is produced by fat cells and appears to play a role in energy storage. Previous research had determined that chemerin is present in higher levels in the blood of obese people. However, Pearson said, it has not been measured in neonates exposed to cigarette smoke.

(Photo by Centophobia/Flickr)

Results showed that chemerin was more prevalent in the skin and isolated cells of infants whose mothers smoked during pregnancy, suggesting that smoking in pregnancy could be leading to changes in the regulation of the genes that play an important role in fat cell development and, by extension, obesity.

“Our work demonstrated that expectant mothers who smoke cigarettes during pregnancy induce distinct changes in chemerin gene expression in their offspring,” Pearson said.

The next step is to reproduce their findings in females since they were not represented in the study. Pearson et al propose to use cells from umbilical cords to do so. The group also hopes to study smoke exposure during pregnancy in genetically modified mice as both chemerin and its receptor can be removed to highlight this pathway more directly. The current and future results could provide a springboard for the development of effective treatments against pediatric and adult obesity in babies born to smokers as well as those exposed to other in utero environmental exposures.

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Source: InfoWars

African refugee women experience healthier pregnancies than women born in the United States, despite receiving less prenatal care, found a recent University at Buffalo study.

Compared to U.S.-born black and white women, African refugee women had fewer pre-pregnancy health risks, fewer preterm births and higher rates of vaginal deliveries. Surprisingly, the refugee women were more likely to delay beginning prenatal care until the second trimester.

The disparity, says the researchers, may be tied to various unhealthy behaviors and practices present within U.S. culture. For African refugee women, acculturation may negatively impact health.

“It is often thought that refugees immigrating to the United States from war-torn nations will experience a better quality of life once here,” says Kafuli Agbemenu, Ph.D., assistant professor in the UB School of Nursing and lead investigator on the study, published in February in the Journal of Women’s Health.

“However, some of the elements of U.S. life such as eating processed food, an increased reliance on cars or buses for transportation, extended inclement weather, a more individualistic society, and drug and alcohol use may, in fact, contribute to African refugee women having poorer reproductive health outcomes.”

Reproductive health disparities between U.S.-born white and black women are well documented, says Agbemenu. However, few comparisons have been made between African refugee women and U.S.-born women.

African refugee women are susceptible to numerous health disparities as a result factors such as socioeconomic status, gender, ethnicity, low-levels of education and language. Another risk-factor specific to their population is the high prevalence of past traumatic experiences.

These risks led researchers to believe African refugee women would have poorer reproductive health outcomes than women born in the U.S. The unexpected results reveal that the healthy immigrant effect—a phenomenon where immigrants experience healthier outcomes than native populations—extends to reproductive health.

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The researchers examined electronic birth certificate data from hospitals within Erie County, an area of Western New York that resettles a large number of refugees. The data contained clinical, psychosocial, socioeconomic and demographic information, as well as the mother’s country of birth.

Women born in Burundi, Democratic Republic of Congo, Eritrea, Rwanda and Somalia were considered of refugee status for the study, due to the large refugee populations in Western New York resettled from these nations.

The data contained information on nearly 60,000 white, almost 17,500 black and close to 800 African refugee women who gave birth from 2007-16. The information was limited to mothers who used Medicaid to cover medical expenses to control for socioeconomic status.

Researchers discovered that African refugee women had significantly less maternal medical risk factors, such as pre-pregnancy hypertension or diabetes, compared to U.S.-born women. Refugee women experienced more vaginal births, and were less likely to undergo cesarean sections or to be medically induced into labor.

Less than 1 percent of refugee women smoked or took illegal drugs during pregnancy, compared to white women (12 percent smoked, 4.5 percent took illegal drugs) and black women (15 percent smoked, 18 percent took illegal drugs).

(Photo by Tatiana Vdb/Flickr)

Refugee women also had the fewest preterm birth (6 percent) compared with white women (9 percent) and black women (13 percent).

While most of the women from all groups began prenatal within the first trimester, African refugee women were more likely to delay prenatal care until the second trimester. Refugee women also received higher amounts of inadequate prenatal care (27 percent) compared to white women (12 percent) and black women (24 percent).

These favorable health outcomes for African refugee women also occurred in spite of the group experiencing higher rates of meconium staining, the earliest stool of an infant that when passed in the womb is a sign of fetal distress.

The high rate of inadequate prenatal care for African refugee women is troubling, says Agbemenu, and indicative of the disconnect between refugee populations and the health care community.

“These women have reported feeling ostracized and marginalized by the medical community,” says Agbemenu. “They are at times hesitant to seek care, and when they do, it is typically at a time when the problem has escalated.”

The development of culturally-targeted reproductive health education is urgently needed, she says. Health care professionals also need to understand that refugee women are likely to have histories of trauma and, therefore, need care delivered from a trauma-informed perspective.

Alex Jones exposes the massive push around the globe to use corporate media to use the New Zealand shooting to smear patriots.

Source: InfoWars

Trimmed eyebrows and make-up aren’t features one would expect to see on a hardened terrorist, but for some of them it is apparently the only way to escape from the Daesh enclave of Baghouz, Syria.

Alleged footage has emerged of the elaborate lengths some presumed Daesh* fighters go to flee the terror group’s final pocket in Syria.

A video shared by a freelance journalist on Twitter shows a purported interview with a bunch of people detained by Kurdish militia during the anti-Daesh offensive in Baghouz.

One of them is wearing a pink scarf and a burqa, a traditional Muslim veil worn by women that covers the body from head to toe except for the eyes.

When told to remove the face covering, it’s discovered that the woman is really a man in disguise, apparently attempting to flee the remains of the self-declared caliphate together with a group of women and children.

The man also appears to be wearing heavy make-up: smokey eyes and high-definition eyebrows.

The interviewer can be heard interrogating another man dressed up as a woman.

The authenticity of the video has yet to be verified.

This is not the first time Daesh militants have been caught “doing drag” to avoid arrest. Last month, Kurdish YPG militia confirmed that some fighters had tried to escape the war zone in southeast Syria using a similar trick.

In 2015, shortly after the beginning of the Russian air campaign against the terrorists, hundreds of fighters in northern Syria reportedly shaved their beards and fled to Turkey. The Russian Air Force then began monitoring terrorist efforts to flee the de facto Daesh capital of Raqqa dressed as civilians.

Later, the Iraqi military temporarily banned the burqa and niqab in liberated Mosul for security reasons amid fears that terrorists were disguising themselves as women in order to escape.

The Syrian Democratic Forces, a mostly-Kurdish US-backed militia, last month launched an operation against Daesh terrorists in Baghouz, a Syrian town near the Iraqi border. The battle against the group’s final enclave is drawing to a close, with jihadi fighters and their families fleeing the besieged town and surrendering to the Kurdish forces.

These refugees — some of whom came to Syria from overseas — are being placed in detention camps, as was the case with Shamima Begum, a British-born girl who fled to the country to marry a Daesh fighter. The UK has recently revoked her citizenship, despite her claims that she’d changed her mind about the organisation.

Not all of them, however, appear willing to follow suit. One of the women detained in Baghouz was reported to have defended militants who raped Yazidis because Yazidi women were “their property”, according to Islam.

Clips have also been circulating of alleged jihadi brides verbally abusing journalists and saluting the terror group.

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Source: InfoWars

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